Dr. Dee and her husband Ken respond to an emergency, flying to rescue baby owls whose parents were killed by an eagle. At Animal house, Dr. Dee's dog becomes a blood donor for a lab with an auto-immune disease, and a cat undergoes stem cell therapy.
Dr. Ross performs a life-altering surgery on a sweet pup given a second chance at life, while Dr. Lavigne examines a prickly pet. After treating an injured owl, Dr. Blue joins Dr. Ross on farm to examine a cute litter of tiny piglets that are sick.
With the holidays approaching, the clinic is busier than ever. Dr. Jeff performs emergency surgery on a dog found tied to a fence. The staff host a fun run to raise money for animals in need. And a stray Pomeranian finds its forever home.
The pressure is on as the students begin their last month as students. Responsibilities are increasing and the students are called upon to step up more than ever.
Dr. Jeff battles to save a Bearded Dragon who is having a seizure. Then Dr. Nichols must figure out why a family's beloved dog is not eating and struggles to breathe. And, Dr. Amy is put to the test when a routine cat neuter turns complicated.
Dr. Dee starts fundraising for a no-kill animal shelter in Fairbanks with a pet tricks competition. A pot-bellied pig named Lilly Lou undergoes a surgery full of surprises. Dr. Dee's long-time friend has a stallion with a possibly deadly tumor.
On the season finale, it's just days until graduation as the students finish up their final rotations. As they prepare for their futures, the students say their goodbyes to Penn Vet, and walk across the stage to finally claim the title V.M.D.
The clock is ticking as Dr. Blue performs an emergency C-section on a mother with two puppies stuck in her uterus, while Dr. Ross and Dr. Lavigne work on pets with serious eye issues.
Dr. Dee takes care of her mother while manning her busy clinic and performing emergency surgery on a Yorkie puppy. She rescues puppies from remote villages in the hopes of finding them homes, and Dr. Terry fights to save one of Santa’s reindeer.
School is in full swing. In just a few months, the students will be doctors, but they must still pass their final rotations. Adding further stress, they're anxiously awaiting match results for next year's internship program.